Movies where women scientists turn themselves into monsters?

The Lazarus Effect with Olivia Wilde.

Death Becomes Her is a rough fit. The potion is magic and the women aren't scientists, but they both willingly drink it and suffer the consequences, becoming more monstrous as the movie goes on.

A few older B-movie fare: * **The Wasp Woman** (1959): scientist experiments on herself with wasp venom, what could go wrong? * **The Reptile** (1966): Female coroner? Check. Serpentine transformations? Check. Cursed Entity? Check! * **Captive Wild Woman** (1943) though she's more experimented on, than experimenter. Honorable mentions to: * **Species**: scientific hubris leads to rampaging alien woman * **Colossal**: >!female scientist discovers she's controlling a giant monster!< * **Attack of the 50 Foot Woman**: exposure to radiation leads to a vengeful woman growing to... you know the rest. * **Lady Frankenstein**: inversion of the original * **Rabid**: experimental medical surgery leads to "unexpected consequences" (technical term) * **Mimic**: Dr Susan Tyler's genetic experiments lead to "unexpected consequences" (when will we learn!) * **Birth/Rebirth**: another take on the Frankenstein story, also **Lisa Frankenstein**, and **The Angry Black Girl and Her Monster** * **Dead Ringers**: the 2023 remake, with Rachel Weisz playing the twin gynecologists, psychological destruction through obsession and extreme codependency * **From Beyond**: Dr Katherine McMichaels starts to, um, "unravel", after choosing to use a machine to see "beyond" normal reality. * **Splice**: Dr. Elsa Kast and her partner create a human-animal hybrid whom she raises like a daughter * **Flatliners**: ensemble group of medical idiots do something they shouldn't, with.. "unexpected consequences". * **Blood of Dracula**: Miss Branding conducts experiments in a girls boarding school to prove that a destructive force lies within every human. With >!"unexpected consequences"!<

Doesn't the evil science lady in Carnosaur (1993) turn into something by the end?

Splice kind of fits what you're talking about, though it's not a straight transformation of the female scientist.  ETA: if you move away from the science based world, you also have possession/occult based transformations like Jennifer's Body and Starry Eyes.

the wasp from ant-man and the wasp kinda fits but she's more like trapped between dimensions than a full monster transformation. splice has sarah polley as the geneticist who creates that weird human-animal hybrid creature, though she doesn't transform herself directly she gets way too involved with her creation in disturbing ways there's also the invisible woman from the 2000 hollow man sequel but that one's pretty forgettable. seems like hollywood really loves the tortured male scientist angle way more than flipping the gender dynamics

Doctor Octopus (Olivia Octavius) in the Spider-verse.

the movie annihilation doesn't have this but the book and it's sequels definitely do and are worth a read. Also The Substance. She's not a scientist herself but it fits the bill otherwise I'd say

Batman and Robin

Superman 3, that cyborg woman

Not a scientist but Titane has a woman turn herself into a bit of a monster

**Mansquito** includes an element of this.

This doesn't meet the prompt exactly, but you still might like it. _Dr. Jekyll and Sister Hyde_ (1971) It's a Hammer horror movie based _The Strange Case Of Dr. Jekyll and Mister Hyde_. Although Jekyll is male, Hyde is a woman and quite monstrous. It's a good time, as it's one of Hammer's best movies from the 70s. That is, the movie suffers from a low budget and a short production schedule, but they did remarkable work within those constraints. Martine Bestwick is Hyde, so there's that.

There's also *Ginger Snaps* where a teen girl turns into a werewolf. Not a scientist, though.

V/H/S Beyond (anthology movie) kinda has this in the last short Stowaway. She's not a scientist but she does find herself in that position very shortly.

Repligator.

There were a couple of Elizabeth Holmes movies that answer this question in a cute way.

It’s actually pretty rare, but stuff like Species kinda hits that vibe in its own way, and Splice flips it with a female scientist getting way too close to her own creation, just not the exact same setup, which is probably why it feels like that trope barely exists for women.

Sonnie's Edge from Love Death & Robots Season 1. Though arguably more an engineer than scientist. Also just by listing it in this thread I've ruined the twist.

I'm gonna pluck that low-hanging fruit and point out that won't be an extensive list because women wouldn't be so wildly irresponsible.

I think The Amazing Spiderman's Dr. Curtis Connors, aka The Lizard is a good start.. :x Edit: WOMEN?! Whoops. Well there's Splice, and Species. ... Teeth? ':3

Ok, not a movie (I know, burn me) but the series The 100 kind of fits. Although it doesn't come to light until a few seasons in.

Dating men is kind of a form of self abuse. Juliet is living her life.... Meets Romeo.... Both dead in a few days. Juliet did nothing but meet some dude. And she's dead.

yep you nailed it totally agree thats the move lol yep thats the universal experience fair point honestly thats just how it goes youre not wrong sounds about right big same thats a solid plan mood honestly could not agree more thats the only way thats a fact thats so real pretty much yeah